heavy-chain variable

heavy-chain variable
вариабельность тяжелой цепи
вариабельный участок тяжелой цепи Ig

English-Russian Biotechnology Glossary. . 2007.

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  • Heavy chain — A heavy chain is the large polypeptide subunit of a protein complex, such as a motor protein (e.g. myosin, kinesin, or dynein) or antibody (or immunoglobulin). A typical antibody is composed of two immunoglobulin (Ig) heavy chains and two Ig… …   Wikipedia

  • Heavy chain disease — Infobox Disease Name = PAGENAME Caption = DiseasesDB = 442 DiseasesDB mult = DiseasesDB2|32226 | ICD10 = ICD10|C|88|1|c|81 ICD10|C|88|2|c|81 ICD9 = ICD9|273.2 ICDO = OMIM = MedlinePlus = eMedicineSubj = med eMedicineTopic = 958 eMedicine mult =… …   Wikipedia

  • Single-chain variable fragment — Rotating scFv fragment with highlighted complementary determining regions (CDRs) …   Wikipedia

  • Single chain variable fragment — (scFv) is a fusion of the variable regions of the heavy and light chains of immunoglobulins, linked together with a short (usually serine, glycine) linker.This chimeric molecule retains the specificity of the original immunoglobulin, despite… …   Wikipedia

  • variable region — n the part of the polypeptide chain of a light or heavy chain of an antibody that ends in a free amino group NH2, that varies greatly in its sequence of amino acid residues from one antibody to another, and that prob. determines the conformation… …   Medical dictionary

  • variable region — noun also variable domain : the part of the polypeptide chain of a light or heavy chain of an antibody that ends in a free amino group −NH2, that varies greatly in its sequence of amino acid residues from one antibody to another, and that prob.… …   Useful english dictionary

  • Chain migration — has multiple meanings. It refers to the social process by which immigrants from a particular town follow others from that town to a particular city or neighborhood, whether in an immigrant receiving country or in a new, usually urban, location in …   Wikipedia

  • Immunoglobulin light chain — Schematic diagram of an typical antibody showing two Ig heavy chains (blue) linked by disulfide bonds to two Ig light chains (green). The constant (C) and variable (V) domains are shown …   Wikipedia

  • H chain — SYN: heavy chain. * * * heavy chain any of the larger polypeptide chains of antibody molecules, two identical heavy chains occurring (with two identical light chains) in each immunoglobulin monomer. The heavy chains determine the immunoglobulin… …   Medical dictionary

  • light chain — n either of the two smaller of the four polypeptide chains that are subunits of antibodies called also L chain compare HEAVY CHAIN * * * any of the smaller polypeptide chains of antibody molecules, two identical light chains occurring (with two… …   Medical dictionary

  • Continuously variable transmission — Transmission types Manual Sequential manual Non synchronous Preselector Automatic Manumatic Semi automatic Electrohydraulic Dual …   Wikipedia


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